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Volume 3, Number 4, Year 2001


Polysomnographic Parameters in Anaemic InfantsBefore and After Transfusion

T.Erler, M.D., J.Oppermann, M.D., and E.Wischniewski, M.D.


Apnoea and periodic breathing are common problems in premature babies,the mecha- nisms are still unclear.But it is well-known that anaemia plays a significant role in the patho- genesis of these disorders.The borders between tolerable hemoglobin-hematocrit reduc- tion in infants and pathological anaemia,which may endanger undisturbed growth in infants,are blurred.Therefore the attempt to observe breathing and circulation in cases of anaemia through the use of a polysomnography is recommended.Irregularities should be remedied after balancing the anaemia.Examinations of 12 infants with anaemia in a sleep research laboratory were compared both before and after transfusion of erythrocytes. While sleep patterns showed no significant changes,certain breathing and circulatory parameters such as the incidence of central apnoea,mean heart rate or mean breathing showed significant drops.A complete polysomnography may be helpful in determining whether a blood transfusion should be undertaken or not.(Sleep and Hypnosis 2001;3(4):144-151)


Keywords: polysomnography, anemic infants, effect of transfusion
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